Manager, Evidence Generation Lead, Systematic Literature Reviews

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the Role  The Evidence Generation Lead, Systematic Literature Reviews is responsible for leading the design, execution, and delivery of systematic literature reviews (SLRs), targeted literature reviews (TLRs), evidence gap assessments, and evidence synthesis activities that support strategic evidence generation and decision-making across the product lifecycle. This role partners closely with Clinical Science, Medical Affairs, Health Economics and Outcomes Research (HEOR), Real-World Evidence (RWE), Biostatistics, and external partners to generate high-quality, decision-ready evidence that informs asset strategy, value demonstration, and scientific communication.  The incumbent will provide scientific and methodological leadership for evidence synthesis activities, ensure adherence to industry standards and best practices, and leverage digital and AI-enabled tools to enhance the efficiency, quality, and scalability of evidence review processes.  How You Will Contribute  Evidence Synthesis Strategy and Execution  Lead end-to-end systematic literature reviews, targeted literature reviews, scoping reviews, and evidence gap assessments to support evidence generation strategies and business priorities.  Define research questions, eligibility criteria, search methodologies, screening approaches, data extraction plans, critical appraisal methods, and synthesis strategies.  Translate stakeholder evidence needs into fit-for-purpose evidence review designs aligned with asset, portfolio, and organizational objectives.  Identify evidence gaps, emerging trends, and opportunities to inform future evidence-generation priorities and research investments.  Ensure consistency, methodological rigor, and compliance with internal standards and external guidance across all review activities.  Cross-Functional Collaboration and Scientific Partnership  Partner with Clinical Science, Medical Affairs, HEOR, RWE, Biostatistics, Market Access, and other stakeholders to support strategic evidence planning and evidence-generation initiatives.  Contribute evidence syntheses supporting publications, congress presentations, value dossiers, health technology assessment submissions, landscape assessments, and strategic planning activities.  Communicate complex evidence findings through clear and actionable reports, presentations, and executive summaries.  Provide scientific consultation regarding literature review methodologies and evidence interpretation.  Vendor Oversight and Operational Excellence